Established in 1949 as a resurrection, it follows the first SC 333 established in 1939, running then as is now. The first SC 333 did extend from its routing in 1940 west to Shirley then southeast to Garnett. In 1941 or 1942, it was extended east to end at SC 631, west of Grays; creating a total of over in length. In 1948, the route was decommissioned. When resurrected, it still left behind Augusta Stage Coach Road, Shirley Road, Stafford Road and S-25-17.