Sicily Express


Sicily Express is an Italian television miniseries created by Ficarra e Picone. It was internationally released on Netflix on 5 December 2025.
The series, produced by Tramp Limited, combines fantasy elements with a Christmas setting, offering an ironic and critical look at Southern Italian society.

Plot

Salvo and Valentino are two Sicilian nurses working in a Milan clinic, commuting between Sicily and Milan on low-cost flights. Their medical director, a Calabrian who pretends to be Milanese, constantly hinders their attempts to return home. One night, thanks to a wish made by Valentino's daughter, they discover a magical dumpster that teleports them from Piazza del Duomo in Milan to their hometown in Sicily, and back again.

Cast

Main

Recurring

  • Sergio Vastano as Sergio Perrone, the medical director
  • Enrico Bertolino as Enrico, the Milanese doctor
  • Adelaide Massari as Aurora, Valentino's daughter
  • Angelo Tosto as Mr. Giacalone, a Sicilian patient in Milan
  • Giorgio Tirabassi as Alfredo, a police detective
  • Angelo Pisani as Andrea, a Milanese nurse
  • Alessia Spinelli as Luisa, a Milanese nurse
  • Alessandro Idonea as Giulio Giacalone, a police officer and Giacalone's son
  • Gianni Federico as Ferdinando, a Sicilian man working in Milan
  • Giovanna Criscuolo as Giovanna, a Sicilian woman working in Milan
  • Vincenzo Ficarra as Mario, a Sicilian boy working in Milan
  • Miriam Galanti as Miriam, the gate attendant
  • Luigi Maria Rausa as Uzeda, the prime minister's secretary
  • Barbara Gallo as Amanda, Valentino's mother-in-law
  • Mimmo Mignemi as Carmelo, Valentino's father-in-law
  • Marco Basile as Guglielmo, Claudia's ex-boyfriend
  • Anna Melato as Mrs. Elvira, the landlady
  • Pino Calabrese as the Head of Forensics

Guest