Secondary and a Subset of Primary Senescent Cells Result from Notch Signalling
Secondary and a Subset of Primary Senescent Cells Result from Notch Signalling is a scholarly work, published in 2018 in ''SSRN Electronic Journal''. The main subjects of the publication include medicine, bioluminescence, primary body, signalling, psychology, biology, single-cell RNA-seq, cellular senescence, Notch signaling pathway, and cell biology. The authors used single-cell transcriptomics in co-culture systems to decipher heterogeneity between primary and secondary Ras-induced senescence and observed two distinct transcriptional trajectories, one marked by Ras and the other by Notch.