San Luis, New MexicoSan Luis is an unincorporated community and census-designated place in Sandoval County, New Mexico, United States. Its population was 59 as of the 2010 census. New Mexico State Road 279 passes through the community.GeographySan Luis is located at. According to the U.S. Census Bureau, the community has an area of, all land.EducationThe community's district is Cuba Independent Schools.