Serotonin–norepinephrine releasing agent

A serotonin–norepinephrine releasing agent is a type of drug which induces the release of serotonin and norepinephrine in the body and/or brain.
Only a few SNRAs are known, examples of which include norfenfluramine, (R)-MDMA, MBDB, and MDAI. Fenfluramine produces norfenfluramine as a major active metabolite and hence is an SNRA similarly. It was formerly used as an appetite suppressant for the treatment of obesity. -MDMA, MBDB, and MDAI are entactogens. Dexfenfluramine is also an SNRA.
A closely related type of drug is a serotonin–norepinephrine reuptake inhibitor.