S1PR2


Sphingosine-1-phosphate receptor 2, also known as S1PR2 or S1P2, is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate.

Function

This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation. It has also been shown to interact with Nogo-A, an neurite outgrowth inhibitor. S1PR2 is expressed in neuronal and vascular cells and is crucial for the migration and growth of developing and injured neuronal and vascular system.

Evolution

Paralogues">Sequence homology">Paralogues

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