Relaxin receptor


The relaxin receptors are a subclass of four closely related G protein-coupled receptors that bind relaxin peptide hormones.
Below is list of human relaxin receptors, their endogenous peptide hormones, and what downstream enzymes are activated or inhibited by the receptor.
receptor/geneligandsactivatesinhibits
relaxin 1, relaxin 2, relaxin 3adenylate cyclase, protein kinase A, protein kinase C,
phosphatidylinositol 3-kinase, extracellular signal-regulated kinases
relaxin 1, relaxin 2, insulin-like 3adenylate cyclase
relaxin 3Erk1/2 signalingadenylate cyclase
relaxin 3, insulin-like 3adenylate cyclase