Rationalization of Racemate Resolution: Predicting Spontaneous Resolution through Crystal Structure Prediction
Rationalization of Racemate Resolution: Predicting Spontaneous Resolution through Crystal Structure Prediction is a scholarly work by John Kendrick and Frank J J Leusen, published in 2007 in ''Crystal Growth & Design''. The main subjects of the publication include hydroxymethyl, resolution, enantiopure drug, lattice energy, molecule, enantiomer, crystallization, stereochemistry, chiral resolution, crystallography, noncovalent bonding, Crystal, chemistry, crystal structure, Crystal structure prediction, and racemate. The work shows that it is possible to predict whether the racemate of a small chiral molecule can be resolved spontaneously, although further advances in the accuracy of lattice energy calculations are required.