6-carboxytetrahydropterin synthase
6-carboxytetrahydropterin synthase , ToyB, ykvK is an enzyme with systematic name 7,8-dihydroneopterin 3'-triphosphate acetaldehyde-lyase . This enzyme catalyses the following reversible chemical reaction.
This enzyme binds Zn2+. It is isolated from the bacteria Bacillus subtilis and Escherichia coli. The stimulation is part of the biosynthesis pathway of queuosine. The enzyme from Escherichia coli can also convert 6-pyruvoyl-5,6,7,8-tetrahydropterin and sepiapterin to 6-carboxy-5,6,7,8-tetrahydropterin.