Pyridoxal kinase
In enzymology, a pyridoxal kinase is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are ATP and pyridoxal, whereas its two products are ADP and pyridoxal 5'-phosphate. A number of other phosphate acceptors can be used in place of pyridoxal to produce the corresponding 5' phosphate, including pyridoxine, pyridoxamine and various derivatives. The 5'-phosphates of pyridoxine and pyridoxamine can be converted to pyridoxal 5'-phosphate by pyridoxine 5′-phosphate oxidase.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:pyridoxal 5'-phosphotransferase. Other names in common use include pyridoxal kinase , pyridoxal 5-phosphate-kinase, pyridoxal phosphokinase, and pyridoxine kinase. This enzyme participates in vitamin B6 metabolism.
Humans have one version of this enzyme encoded by the gene PDXK.