Pseudonocardiaceae


The Pseudonocardiaceae are a family of bacteria in the order Actinomycetales and the only member of the suborder Pseudonocardineae.

Genomics

The species within the family Pseudonocardiaceae form a distinct clade in phylogenetic trees based on concatenated protein sequences. Additionally, Nakamurella multipartite, currently part of the order Frankiales, also formed a clade with the Pseudonocardiaceae species in 100% of the bootstrap replications of the phylogenetic trees. A conserved signature indel has been identified which is found in N. multipartite and all but one of the Pseudonocardiaceae species. This one-amino-acid insertion in UMP kinase serves to both provide a molecular marker for nearly all of the Pseudonocardiaceae and suggests N. multipartite is closely related to this group. Some evidence also suggests the orders Pseudonocardiales and Corynebacteriales are closely related. Several conserved signature indels have been identified which are found in both Pseudonocardiales and Corynebacteriales, including a three-amino-acid insertion in a conserved region of UDP-galactopyranose mutase. This insertion is also present in N. multipartite and Geodermatophilus obscurus, another member of Frankiales. Additionally, five conserved signature proteins have been identified which are found only in the orders Pseudonocardiales and Corynebacteriales. Homologs of the proteins are generally found in N. multipartite and G. obscurus, providing additional evidence of these two species being closely related to the orders Pseudonocardiales and Corynebacteriales.

Genera

Pseudonocardiaceae comprises the following genera:Actinoalloteichus Tamura et al. 2000Actinocrispum Hatano et al. 2016Actinokineospora Hasegawa 1988Actinomycetospora Jiang et al. 2008Actinophytocola Indananda et al. 2010Actinopolyspora Gochnauer et al. 1975 Actinorectispora Quadri et al. 2016Actinosynnema Hasegawa et al. 1978 Allokutzneria Labeda and Kroppenstedt 2008Allosaccharopolyspora Teo et al. 2021Amycolatopsis Lechevalier et al. 1986Bounagaea Meklat et al. 2015Crossiella Labeda 2001Gandjariella Ningsih et al. 2019Goodfellowiella Labeda et al. 2008Haloactinomyces Lai et al. 2017Haloechinothrix Tang et al. 2010Halopolyspora Lai et al. 2014Halosaccharopolyspora Teo et al. 2021Herbihabitans Zhang et al. 2016Kibdelosporangium Shearer et al. 1986Kutzneria Stackebrandt et al. 1994Labedaea Lee 2012Lentzea Yassin et al. 1995Longimycelium Xia et al. 2013Prauserella Kim and Goodfellow 1999Pseudonocardia Henssen 1957 Qaidamihabitans Tian et al. 2022Saccharomonospora Nonomura and Ohara 1971 Saccharopolyspora Lacey and Goodfellow 1975 Saccharothrix Labeda et al. 1984Salinifilum Moshtaghi Nikou et al. 2017Sciscionella Tian et al. 2009Solihabitans Jin et al. 2022Streptoalloteichus Tomita et al. 1987Tamaricihabitans Qin et al. 2015Thermocrispum Korn-Wendisch et al. 1995Thermotunica Wu et al. 2014Umezawaea Labeda and Kroppenstedt 2007

Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature. The phylogeny is based on whole-genome analysis.