3,4-Dihydroxybenzaldehyde


3,4-Dihydroxybenzaldehyde, also known as protocatechuic aldehyde, is a phenolic aldehyde, a compound released from cork stoppers into wine. It is an isomer of 2,4-dihydroxybenzaldehyde.
This molecule can be used as a precursor in the vanillin synthesis by biotransformation by cell cultures of Capsicum frutescens, a type of Chili pepper. It is also found in the mushroom Phellinus linteus.

Pharmacological effects

Protocatechuic aldehyde regulates G protein-coupled estrogen receptor-1 and exhibits protective effects in endothelial dysfunction and atherosclerosis.