Persulfidation

Persulfidation is a type of post-translational modification of proteins involving addition of a sulfur molecule onto a reactive thiol group of a cysteine residue. Persulfidation occurs in plants, animals, and throughout all kingdoms. It is a redox mechanism that regulates diverse biological processes in hydrogen sulfide signaling by regulating protein functions and/or subcellular localizations.
The added sulfur atom are in a chain or TCEP, biological reducing agents such as glutathione, and proteins such as thioredoxin or glutaredoxin.