Signaling peptide receptor
Signaling peptide receptor is a type of receptor which binds one or more signaling peptides or signaling proteins.
An example is the tropomyosin receptor kinase B, which is bound and activated by the neurotrophic protein brain-derived neurotrophic factor. Another example is the μ-opioid receptor, which is bound and activated by the opioid peptide hormone β-endorphin.
Adiponectin receptor
AdipoR1
- Agonists
- * Peptide
- ** Adiponectin
- ** ADP-355
- ** ADP-399
- * Non-peptide
- ** AdipoRon
- ** (–)-Arctigenin
- ** Arctiin
- ** Gramine
- ** Matairesinol
- Antagonists
- * Peptide
- ** ADP-400
AdipoR2
- Agonists
- * Peptide
- ** Adiponectin
- ** ADP-355
- ** ADP-399
- * Non-peptide
- ** AdipoRon
- ** Deoxyschizandrin
- ** Parthenolide
- ** Syringing
- ** Taxifoliol
- Antagonists
- * Peptide
- ** ADP-400
Bradykinin receptor
- Agonists
- * Bradykinin
- * Kallidin
- Antagonists
- * FR-173657
- * Icatibant
- * LF22-0542
Calcitonin gene-related peptide receptor
- Agonists
- * Amylin
- * CGRP
- * Pramlintide
- Antagonists
- * Atogepant
- * BI 44370 TA
- * CGRP (8-37)
- * MK-3207
- * Olcegepant
- * Rimegepant
- * SB-268262
- * Telcagepant
- * Ubrogepant
- Antibodies
- * Eptinezumab
- * Erenumab
- * Fremanezumab
- * Galcanezumab
Cholecystokinin receptor
CCKA
- Agonists
- * Cholecystokinin
- Antagonists
- * Amiglumide
- * Asperlicin
- * Devazepide
- * Dexloxiglumide
- * Lintitript
- * Lorglumide
- * Loxiglumide
- * Pranazepide
- * Proglumide
- * Tarazepide
- * Tomoglumide
CCKB
- Agonists
- * Cholecystokinin
- * CCK-4
- * Gastrin
- * Pentagastrin (CCK-5)
- Antagonists
- * Ceclazepide
- * CI-988 (PD-134308)
- * Itriglumide
- * L-365,360
- * Netazepide
- * Proglumide
- * Spiroglumide
Unsorted
- Antagonists
- * Nastorazepide
Corticotropin-releasing hormone receptor
CRF1
- Agonists
- * Cortagine
- * Corticorelin
- * Corticotropin-releasing hormone
- * Sauvagine
- * Stressin I
- * Urocortin
- Antagonists
- * Antalarmin
- * Astressin-B
- * CP-154,526
- * Emicerfont
- * Hypericin
- * LWH-234
- * NBI-27914
- * NBI-74788
- * Pexacerfont
- * R-121919
- * TS-041
- * Verucerfont
CRF2
- Agonists
- * Corticorelin
- * Corticotropin-releasing hormone
- * Sauvagine
- * Urocortin
- Antagonists
- * Astressin-B
Endothelin receptor
- Agonists
- * Endothelin 1
- * Endothelin 2
- * Endothelin 3
- * IRL-1620
- * Sarafotoxin
- Antagonists
- * A-192621
- * Ambrisentan
- * Aprocitentan
- * Atrasentan
- * Avosentan
- * Bosentan
- * BQ-123
- * BQ-788
- * Clazosentan
- * Darusentan
- * Edonentan
- * Enrasentan
- * Fandosentan
- * Feloprentan
- * Macitentan
- * Nebentan
- * Sitaxentan
- * Sparsentan
- * Tezosentan
- * Zibotentan
Galanin receptor
GAL1
- Agonists
- * Galanin
- * Galanin (1-15)
- * Galanin-like peptide
- * Galmic
- * Galnon
- * NAX 810-2
- Antagonists
- * C7
- * Dithiepine-1,1,4,4-tetroxide
- * Galantide (M15)
- * M32
- * M35
- * M40
- * SCH-202596
GAL2
- Agonists
- * Galanin
- * Galanin (1-15)
- * Galanin (2-11)
- * Galanin-like peptide
- * Galmic
- * Galnon
- * J18
- * NAX 810-2
- Antagonists
- * C7
- * Galantide (M15)
- * M32
- * M35
- * M40
- * M871
GAL3
- Agonists
- * Galanin
- * Galanin (1-15)
- * Galmic
- * Galnon
- Antagonists
- * C7
- * Galantide (M15)
- * GalR3ant
- * HT-2157
- * M32
- * M35
- * M40
- * SNAP-37889
- * SNAP-398299
Glucagon-like peptide receptor
GLP-1
- Agonists
- * Albiglutide
- * Beinaglutide
- * Dulaglutide
- * Efpeglenatide
- * Exenatide
- * GLP-1
- * Langlenatide
- * Liraglutide
- * Lixisenatide
- * Oxyntomodulin
- * Pegapamodutide
- * Semaglutide
- * Taspoglutide
GLP-2
- Agonists
- * Apraglutide
- * Elsiglutide
- * Glepaglutide
- * GLP-2
- * Teduglutide
Others
Glucagon receptor
- Agonists
- * Dasiglucagon
- * Glucagon
- * Oxyntomodulin
- Antagonists
- * Adomeglivant
- * L-168,049
- * LGD-6972
- Propeptides
- * Preproglucagon
- * Proglucagon
Insulin receptor
- Agonists
- * Chaetochromin (4548-G05)
- * Insulin-like growth [factor 1]
- * Insulin-like growth factor 2
- * Insulin
- * Insulin aspart
- * Insulin degludec
- * Insulin detemir
- * Insulin glargine
- * Insulin glulisine
- * Insulin lispro
- * Mecasermin
- * Mecasermin rinfabate
- Antagonists
- * BMS-754807
- * S661
- * S961
- Kinase inhibitors
- * Linsitinib
- Antibodies
- * Xentuzumab
KiSS1-derived peptide receptor
- Agonists
- * Kisspeptin (kisspeptin-54, metastin)
- * Kisspeptin-10
- * KISS1-305
- * MVT-602 (RVT-602, TAK-448)
- * TAK-683
- Antagonists
- * Kisspeptin-234
Leptin receptor
- Agonists
- * Leptin
- * Metreleptin
Melanin-concentrating hormone receptor
MCH1
- Agonists
- * Melanin-concentrating hormone
- Antagonists
- * ATC-0065
- * ATC-0175
- * GW-803430
- * NGD-4715
- * SNAP-7941
- * SNAP-94847
MCH2
- Agonists
- * Melanin-concentrating hormone
Neuropeptide FF receptor
- Agonists
- * Neuropeptide AF
- * Neuropeptide FF
- * Neuropeptide SF (RFRP-1)
- * Neuropeptide VF (RFRP-3)
- Antagonists
- * BIBP-3226
- * RF9
Neuropeptide S receptor
- Agonists
- * Neuropeptide S
- Antagonists
- * ML-154
- * SHA-68
Neuropeptide Y receptor
Y1
- Agonists
- * Neuropeptide Y
- * Peptide YY
- Antagonists
- * BIBO-3304
- * BIBP-3226
- * BVD-10
- * GR-231118
- * PD-160170
Y2
- Agonists
- * 2-Thiouridine 5'-triphosphate
- * Neuropeptide Y
- * Neuropeptide Y (13-36)
- * Peptide YY
- * Peptide YY (3-36)
- Antagonists
- * BIIE-0246
- * JNJ-5207787
- * SF-11
Y4
- Agonists
- * GR-231118
- * Neuropeptide Y
- * Pancreatic polypeptide
- * Peptide YY
- Antagonists
- * UR-AK49
Y5
- Agonists
- * BWX-46
- * Neuropeptide Y
- * Peptide YY
- Antagonists
- * CGP-71683
- * FMS-586
- * L-152,804
- * Lu AA-33810
- * MK-0557
- * NTNCB
- * Velneperit (S-2367)
Neurotensin receptor
NTS1
- Agonists
- * Neurotensin
- * Neuromedin N
- Antagonists
- * Meclinertant
- * SR-142948
NTS2
- Agonists
- * Neurotensin
- Antagonists
- * Levocabastine
- ** SR-142948
Prolactin receptor
Parathyroid hormone receptor
- Agonists
- * Abaloparatide
- * Parathyroid hormone
- * Parathyroid hormone-related protein (PTHrP)
- * Semparatide
- * Teriparatide
Relaxin receptor
- Agonists
- * Insulin-like factor 3
- * Relaxin
- * Serelaxin
Thyrotropin-releasing hormone receptor
- Agonists
- * Azetirelin
- * JTP-2942
- * Montirelin
- * Orotirelin
- * Posatirelin
- * Protirelin
- * Rovatirelin
- * RX-77368 (thymoliberin)
- * Taltirelin
- * TRH (TRF)
Thyrotropin receptor
- Agonists
- * Thyrotropin alfa
- * TSH (thyrotropin)
Vasoactive intestinal peptide receptor and Pituitary adenylate cyclase-activating peptide
VIPR1
- Agonists
- * Peptide
- ** Bay 55-9837
- ** LBT-3393
- ** PACAP
- ** VIP
VIPR2
PAC1
- Agonists
- * PACAP
- * PACAP (1-27)
- * PACAP (1-38)
- Antagonists
- * PACAP (6-38)
Unsorted
Others
- Endogenous
- * Adrenomedullin
- * Apelin
- * Asprosin
- * Bombesin
- * Calcitonin
- * Carnosine
- * CART
- * CLIP
- * DSIP
- * Enteroglucagon
- * Formyl peptide
- * GALP
- * GIP
- * GRP
- * Integrin ligands
- ** collagens
- ** fibrinogen
- ** fibronectin
- ** laminins
- ** ICAM-1
- ** ICAM-2
- ** osteopontin
- ** VCAM-1
- ** vitronectin
- * Kininogens
- * Motilin
- * Natriuretic peptides
- ** ANP
- ** BNP
- ** CNP
- ** urodilatin
- * Nesfatin-1
- * Neuromedin B
- * Neuromedin N
- * Neuromedin S
- * Neuromedin U
- * Obestatin
- * Osteocalcin
- * Resistin
- * Secretin
- * Thymopoietin
- * Thymosins
- * Thymulin
- * Urotensin-II
- * VGF
- Exogenous
- * Lifitegrast