PCS
- Communist Party of El Salvador
- ISU Judging System
- List of patrol vessels of the United States Navy
- PC (disambiguation)
- Pacific Central Station
- Pacific Championship Series
- Pacific Collegiate School
- Parsec
- Partitioning Communication System
- Pelvic congestion syndrome
- Periphere Computer Systeme
- Permanent change of station
- Personal Clothing System
- Personal Communications Service
- Personal computer
- Petaluma City Schools
- PhillyCarShare
- Photo City Sagamihara
- Photon correlation spectroscopy
- Physical coding sublayer
- Picture communication symbols
- Pinball Construction Set
- Plastic-clad silica fiber
- Polish Council of State
- Portland Center Stage
- Post-concussion syndrome
- Postcholecystectomy syndrome
- PotashCorp
- Precordial catch syndrome
- Presbyterian Christian School
- Prime Cabinet Secretary
- Process control system
- Professional Children's School
- Profile connection space
- Provincial Civil Service (disambiguation)
- Provo Canyon School
- Public and Commercial Services Union
- Pueblo City Schools
- Sammarinese Communist Party