Para-Bromoamphetamine


para-Bromoamphetamine, also known as 4-bromoamphetamine, is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent and produces stimulant effects.
Another related compound is para-bromomethamphetamine known by the codename V-111.

Pharmacology

PBA has been found to be a monoamine [oxidase A] inhibitor, with an of 1,500nM.

Neurotoxicity

Like most other Arene [substitution patterns|para]-substituted amphetamines, PBA can be neurotoxic and may deplete the brain of 5-hydroxyindoles for at least a week.

6-BAT

Given that 6-CAT is a non-neurotoxic version of para-chloroamphetamine, it is worth considering 6-BAT as well.
The chemical name for this is 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-amine or 6-bromo-2-aminotetralin . The synthesis method is disclosed. The precursor is called 6-Bromo-2-tetralone .