6-CAT


6-Chloro-2-aminotetralin is a drug which acts as a selective [serotonin releasing agent] and is a putative entactogen in humans. It is a rigid analogue of para-chloroamphetamine.
According to Nichols et al., 6-CAT is a non-neurotoxic analog of PCA.
Other related compounds that are creditworthy of mention include & 5,6-DCAT . These compounds were invented by Bryan Molloy. These can be thought to be rigid analogs of 3,4-Dichloroamphetamine and might be predicted to be similarly non-neurotoxic. A positional isomer of the aforementioned two compounds is also known to exist in the literature with a 5,8-dichloro substitution pattern. The compound depicted in the latter case is with the spirodecanone pharmacophore.
It is worth pointing out that the precursor used in the synthesis of 6-CAT is called 6-Chloro-2-tetralone . This compound is actually the starting material in the synthesis of Bexlosteride.