Oxazolidinone


The oxazolidones and isoxazolidones are a set of six isomeric five-membered heterocyclic compounds consisting of a carbonyl group, an oxygen atom, a nitrogen atom with a hydrogen atom attached, and two methylene groups. The chemicals differ in the relative position of these groups around the ring, which results in different functional group combinations.
2-Oxazolidinone4-Oxazolidinone5-Oxazolidinone
3-Isoxazolidinone4-Isoxazolidinone5-Isoxazolidinone

2-Oxazolidinone is the parent compound of several protein synthesis inhibitor antibiotics and the Evans chiral auxiliaries for aldol reactions. Cycloserine is an antibiotic based on the 3-isoxazolidone parent.