Primetime Emmy Award for Outstanding Guest Actor in a Comedy Series
This is a list of winners and nominees of the Primetime Emmy Award for Outstanding Guest Actor in a Comedy Series. Prior to 1988 the category was not gender specific, thus was called Outstanding Guest Performer in a Comedy Series. These awards, like the other "Guest" awards, are not presented at the Primetime Emmy Award ceremony, but rather at the Creative Arts Emmy Award ceremony.
Beginning with the 77th Primetime Emmy Awards, performers are no longer eligible in guest acting categories if they were previously nominated for a lead or supporting award for playing the same character role in the same series.
Nathan Lane has received the most nominations in this category with 7, winning once for the Hulu comedy series Only Murders in the Building in 2022. Mel Brooks has received the most wins in this category for his role in the NBC comedy series Mad About You in 1997, 1998, and 1999.
Individuals with multiple wins
;3 wins;2 wins
Programs with multiple awards
;7 awardsSaturday Night Live;4 awardsMad About You
;3 awardsMurphy Brown Will & Grace
;2 awardsFrasier
- ''Monk''
Individuals with multiple nominations
;7 nominations;5 nominations
;4 nominations
;3 nominations
- Alec Baldwin
- Jon Bernthal
- Bobby Cannavale
- Louis C.K.
- John Cleese
- Bill Hader
- Luke Kirby
- Anthony LaPaglia
- Bob Newhart
- Justin Timberlake
- Hank Azaria
- Beau Bridges
- Roscoe Lee Browne
- Steve Buscemi
- Sid Caesar
- Dave Chappelle
- Tim Conway
- Bryan Cranston
- Matt Damon
- Danny DeVito
- David Duchovny
- Herb Edelman
- Jimmy Fallon
- Victor Garber
- Will Geer
- Lin-Manuel Miranda
- Brad Pitt
- Carl Reiner
- Sam Richardson
- Martin Sheen
- Jay Thomas
- Bradley Whitford
Programs with multiple nominations
;31 nominationsSaturday Night Live;14 nominations30 Rock
;13 nominationsFrasier
;9 nominationsWill & Grace
;8 nominationsThe Golden Girls
;7 nominationsThe Cosby ShowMad About YouMurphy Brown
;6 nominationsThe BearFriendsModern Family
;5 nominationsCurb Your EnthusiasmSeinfeldThe Studio
;4 nominationsThe Marvelous Mrs. MaiselVeep
;3 nominationsThe Big Bang TheoryCheersDream OnEverybody Loves RaymondExtrasGirlsThe Larry Sanders ShowNurse JackieOnly Murders in the BuildingTed Lasso
;2 nominations3rd Rock from the SunCoachGleeHacksLife with BonnieMonkMy Name Is EarlTransparent
- ''The Wonder Years''