Neuronal ensemble-specific DNA methylation strengthens engram stability
Neuronal ensemble-specific DNA methylation strengthens engram stability is a scholarly work by Kubra Gulmez Karaca, Christian Thome, and Ana M. M. Oliveira, published in 2020 in ''Nature Communications''. The main subjects of the publication include memory consolidation, engram, hippocampus, microglia, biology, recall, epigenetics, dentate gyrus, psychology, DNA methylation, neuroscience, and synaptic plasticity. The authors found that Dnmt3a2 upregulation enhances memory performance in mice and improves the fidelity of reconstitution of the original neuronal ensemble upon memory retrieval.