List of highways numbered 220
Route 220 or Highway 220 may refer to:
Australia
Canada
- Manitoba Provincial Road 220
- Newfoundland and Labrador Route 220
- Quebec Route 220
- Saskatchewan Highway 220
China
Costa Rica
Japan
United Kingdom
- A220 road
- B220 road
United States
- Interstate 220
- U.S. Route 220
- Arkansas Highway 220
- California [State Route 220]
- Georgia State Route 220
- Iowa Highway 220
- Kentucky Route 220
- Maine State Route 220
- Route 220 (Connecticut–Massachusetts)
- Minnesota [State Highway 220]
- New Mexico [State Road 220]
- New York State Route 220
- Ohio State Route 220
- Tennessee State Route 220
- Texas State Highway 220
- Utah State Route 220
- Washington State Route 220
- Wyoming Highway 220