Murid gammaherpesvirus 4


Murid gammaherpesvirus 4 is a species of virus in the genus Rhadinovirus. It is a member of the subfamily Gammaherpesvirinae in the family Herpesviridae. This species infects mice via the nasal passages and causes an acute infectious mononucleosis-like syndrome with elevated levels of leukocytes, and shifts in the relative proportion of lymphocytes along with the appearance of atypical mononuclear cells. Murid gammaherpesvirus 4 currently serves as a model for study of human gammaherpesvirus pathogenesis.

Strains

Seven strains of Murid gammaherpesvirus 4 have been isolated, including the following six:
  • MuHV-Šum
  • MuHV-60
  • MuHV-68
  • MuHV-72
  • MuHV-76
  • MuHV-4556