Model Testing in Radioligand/Receptor Interaction by Monte Carlo Simulation
Model Testing in Radioligand/Receptor Interaction by Monte Carlo Simulation is a scholarly work, published in 1983 in ''Journal of Receptors and Signal Transduction''. The main subjects of the publication include mathematics, saturation, pharmacology, radioligand, regression analysis, G protein-coupled recepteishon, non-linear least squares, statistics, beta2-adrenergic agonist, estimation theory, Monte Carlo method, curve fitting, Scatchard equation, nonlinear system, chemistry, nonlinear regression, linear regression, drug design, and statistical physics. It was found that linear regression analysis from the transformed data in the Scatchard plot yielded generally less accurate parameter estimates than nonlinear regression analysis of untransformed data.