Graphic presentation and analysis of inhibition data from ligand-binding experiments
Graphic presentation and analysis of inhibition data from ligand-binding experiments is a scholarly work, published in 1986 in ''Analytical Biochemistry''. The main subjects of the publication include ligand, half maximal inhibitory concentration, chemistry, monoclonal antibody therapy, signaling receptor, drug design, G protein-coupled recepteishon, ligand binding, radioligand, and Scatchard equation. The authors describe an alternate plot of the form B = -(B X I)(1/IC50) + B0 (where B is the concentration of bound radioligand and B0 is the concentration of radioligand bound in the absence of the inhibitor).