Meromyosin


Meromyosin is the monomeric unit, polymerised to form myosin. With regards to human anatomy myosin and actin constitute the basic functional unit of a muscle fiber, called sarcomere, playing role in muscle contraction as well as .
Biochemically viewed meromyosin form subunits of the actin-associated motor protein, myosin, as commonly obtained by trypsin proteolysis. Meromyosin consists ofthree different parts, The globular head, The tail, The short arm. Following this proteolysis, two types of meromyosin are formed: heavy meromyosin and .
has a long, straight portion called the “tail” region. Heavy meromyosin is a protein chain terminating into a and a /cross bridge. HMM consists of two subunits, Heavy Meromyosin Subunit 1 and 2. The majority of myosin activity is concentrated in HMMS-1. HMMS-1 has an actin binding site and ATP binding site that determines the rate of muscle contraction when muscle is stretched.
Light and heavy meromyosin are subunits of myosin filaments.