MSD
- Commonwealth of Independent States
- MSD (company)
- MSD Capital
- MSD Ignition
- MSD Super Disk
- Macromolecular Structure Database
- Magnetic switchable device
- Mahendra Singh Dhoni
- Major hypersomnolence disorder
- Manchester Metropolitan University
- Marjory Stoneman Douglas High School
- Mars solar date
- Maryland School for the Deaf
- Masjid railway station
- Mass spectrometric detector
- Mass storage device
- Master Scuba Diver
- Mean Shortest Distance
- Mean signed deviation
- Mean squared displacement
- Memory Stick Duo
- Metro de Santo Domingo
- Microsoft Diagnostics
- Milford School District
- Ministry of Social Development (New Zealand)
- Mission Science Division
- Missouri School for the Deaf
- Mobile Security Deployments
- Modem Sharing Device
- Moorside railway station
- Moscow School District
- Moscow Summer Time
- Most significant digit
- Msida
- Multiple sulfatase deficiency
- Musculoskeletal disorders
- Regulation of ship pollution in the United States
- SD Card
- Searcy County School District
- Stoneman Douglas High School shooting
- Syrian Democratic Council
- Typing
- X25XE
- Young Social Democrats (Czech Republic)
- Young Social Democrats (Slovakia)