Lysine 6-dehydrogenase
Lysine 6-dehydrogenase is an enzyme with systematic name L-lysine:NAD+ 6-oxidoreductase . This enzyme catalyses the following overall chemical reaction
The two substrates of this enzyme are L-lysine and oxidised nicotinamide adenine dinucleotide. Its products are -2,3,4,5-tetrahydropyridine-2-carboxylic acid, ammonia, reduced NADH, and a proton.
The enzyme is highly specific for L-lysine as substrate, although S-(2-aminoethyl)-L-cysteine can act as a substrate, but more slowly.