List of highways numbered 380Route 380 or Highway 380 may refer to:CanadaNew Brunswick Route 380Newfoundland and Labrador Route 380Japan Japan National Route 380United States Interstate 380 U.S. Route 380 Arizona State Route 380 Arkansas Highway 380 Georgia State Route 380 Louisiana Highway 380 Maryland Route 380 New York State Route 380 Ohio State Route 380 Oregon Route 380 Pennsylvania Route 380 Puerto Rico Highway 380 Tennessee State Route 380