Liquiritigenin


Liquiritigenin is a flavanone that was isolated from Glycyrrhiza uralensis, and is found in a variety of plants of the Glycyrrhiza genus, including Glycyrrhiza glabra. It is an estrogenic compound which acts as a selective agonist of the Estrogen [receptor beta|ERβ] subtype of the estrogen receptor, though it is also reported to act as an ERα partial agonist at sufficient concentrations. It also has a choleretic effect.
Liquiritigenin,NADPH:oxygen [oxidoreductase (hydroxylating, aryl migration)] is an enzyme that uses liquiritigenin, O2, NADPH and H+ to produce 2,7,4'-trihydroxyisoflavanone, H2O, and NADP+.