José Vargas
José Vargas or Jose Vargas may refer to:
- José Vargas (baseball), Cuban baseball player
- José Vargas (basketball), Dominican basketball player
- Jose "Joe" Vargas, American YouTuber also known as "Angry Joe"
- Jose Antonio Vargas, journalist, filmmaker and immigration rights activist
- José Augusto Vargas, Peruvian politician
- José Gregorio Vargas, Venezuelan basketball player
- José Lino Vargas, Chilean politician
- José MarÃa Vargas, President of Venezuela from 1835 to 1836
- José Dorángel Vargas Gómez, Venezuelan serial killer and cannibal