James Hume
James Hume may refer to:
- James Hume (architect), architect in Sydney, Australia
- James Hume (cricketer), Scottish-born New Zealand cricketer
- James Hume (magistrate), British magistrate and political commentator in Calcutta
- James Hume (mathematician), Scottish mathematician given credit for introducing the modern exponential notation
- James Hume (superintendent), New Zealand asylum superintendent
- James Hume (rugby union), Irish rugby union player
- James B. Hume, lawman in the American West
- James Deacon Hume, English official, economic writer and advocate of free trade
- Jim Hume, Scottish Liberal Democrat politician