JWH-122


JWH-122 is a synthetic cannabimimetic that was discovered by John W. Huffman. It is a methylated analogue of JWH-018. It has a Ki of 0.69 nM at CB1 and 1.2 nM at CB2.
In January 2015, over 40 people were reportedly sickened after eating a holiday bread called Rosca de reyes purchased at a bakery in Santa Ana, California, that was laced with JWH-122.
pharmacology
compared with thc and its much more reduced binding affinity of just 40.4nM and therefore its ability to even reduce signalling then bodyown endocannabinoids, jwh 177 and other full agonists especially those with very potent binding affinitys of the >35-fold strongness of thc, synthetic cannabinoids can activade the endocanabinoid-system of the human body excessively.

Legal status

Australia

JWH-122 is considered a Schedule 9 prohibited substance in Australia under the Poisons Standard. A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.

China

As of October 2015 JWH-122 is a controlled substance in China.

United States

In the United States, JWH-122 is a Schedule I Controlled Substance.