Issues with threshold masking in voxel-based morphometry of atrophied brains


Issues with threshold masking in voxel-based morphometry of atrophied brains is a scholarly work by Gerard R. Ridgway, Jason D. Warren, Nick C. Fox, and Sebastien Ourselin, published in 2008 in ''NeuroImage''. The main subjects of the publication include voxel, voxel-based morphometry, neuroanatomy, masking, computer science, connectome, diffusion-weighted magnetic resonance imaging, computer vision, pattern recognition, magnetic resonance imaging, and artificial intelligence. The authors show that one of the most commonly used strategies for defining this mask runs a major risk of excluding from the analysis precisely those voxels where the subjects' brains were most vulnerable to atrophy.

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