Isom (surname)
Isom is a surname and occasionally a given name. Notable people with the name include:
- Anne Williams-Isom, American government official, academic, lawyer, and nonprofit executive
- Cedric Isom, American-Rwandan basketball player
- Daniel Isom, American academic and police officer
- Harriet Winsar Isom, American foreign service officer
- Lori L. Isom, American pharmacologist
- Mary Frances Isom, American librarian
- Mike Isom, American football coach
- Mo Isom, American soccer player
- Ray Isom, American football player
- Rickey Isom, American football player
- Sarah McGehee Isom, American orator