Isaac Davis

• Isaac Davis (soldier), Revolutionary War Minuteman captain
• Isaac Davis (advisor), Welsh advisor to Kamehameha I
• Isaac Davis (lawyer), lawyer active in Worcester, Massachusetts
• Isaac Davis (American football), American football player
• Ike Davis, American baseball first baseman
• Ike Davis (shortstop), American baseball shortstop
• Isaac Mortimer Davis, the protagonist of Woody Allen's 1979 film Manhattan