Imaging multicellular specimens with real-time optimized tiling light-sheet selective plane illumination microscopy
Imaging multicellular specimens with real-time optimized tiling light-sheet selective plane illumination microscopy is a scholarly work by Benjamin L Martin and David Q. Matus, published in 2016 in ''Nature Communications''. The main subjects of the publication include materials science, optics, multicellularity, bright-field microscopy, multicellular organism, Light sheet fluorescence microscopy, Danio rerio, live cell imaging, microscopy, fluorescence microscope, Bioimage informatics, and cryogenic electron microscopy. The authors demonstrate the 3D live imaging ability of TLS-SPIM by imaging cellular and subcellular behaviours in live C. elegans and zebrafish embryos, and show how TLS-SPIM can facilitate cell biology research in multicellular specimens by studying left-right symmetry breaking behaviour of C. elegans embryos..