Houra Merrikh
Houra Merrikh is an Iranian-American microbiologist. She is a full professor at Vanderbilt University in the Department of Biochemistry. Her field of work is antibiotic resistance and bacterial evolvability. She also has 2 children Jasper and Jasmine Merrikh.
Early life and education
Merrikh was born in Iran and fled the country during the Iran-Iraq War, she was raised in Turkey. At age 16, she was sent to Texas to continue her education. She naturalized as a citizen of the United States in 2003. After attending community college in Texas, she enrolled at the University of Houston and later Boston University.She obtained a M.S. degree in 2006 and a Ph.D. in 2009 from Brandeis University, and worked with biologist Susan Lovett. She was a National Institutes of Health postdoctoral fellow at the Massachusetts Institute of Technology from 2009 until 2011.
Career
In 2009, she was appointed Assistant Professor of Microbiology in the Department of Health and Sciences at the University of Washington. In 2015, she discovered a bacterial protein called Mutation Frequency Decline quickens the bacterial mutation process. In January 2019, she was appointed full Professor in the Department of Biochemistry at Vanderbilt University.Her work researches ways to slow the rate of bacterial mutations and to block their evolution. In 2017, she led the research group to help bacteria survive hostile environments and resist antibiotics, done through disrupting DNA replication in order to boost the rate of gene mutations.
She has discovered the first compound that inhibits the evolution of antimicrobial resistance through transcription-coupled nucleotide excision repair across highly divergent bacterial pathogens. https://pubmed.ncbi.nlm.nih.gov/38911259/.