List of highways numbered 385
Route 385, or Highway 385, may refer to:
Canada
- New Brunswick Route 385
- Quebec Route 385
Japan
- Japan National Route 385
United States
- Interstate 385
- U.S. Route 385
- Arkansas Highway 385
- Florida State Road 385
- Georgia State Route 385
- Maryland Route 385
- New York State Route 385
- * New York State Route 385
- Ohio State Route 385
- South Carolina Highway 385
- Tennessee State Route 385
- Texas:
- * Texas State Highway Loop 385
- * Ranch to Market Road 385
- Virginia State Route 385