High-resolution mapping of transcription factor binding sites on native chromatin
High-resolution mapping of transcription factor binding sites on native chromatin is a scholarly work by Sivakanthan Kasinathan, Guillermo A Orsi, Gabriel E Zentner, Kami Ahmad, and Steven Henikoff, published in 2013 in ''Nature Methods''. The main subjects of the publication include biology, micrococcal nuclease, deoxyribonucleic acid, gene, genetics, ChIP on chip, ChIA-PET, computational biology, cell biology, ChIP-sequencing, chromatin immunoprecipitation, ribosome, nuclease, transcription factor, chromatin, DNA-binding protein, and polyploidy. The authors describe a method to profile TF binding at high resolution without cross-linking.