Glucuronolactone reductase

In enzymology, a glucuronolactone reductase is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are L-gulono-1,4-lactone and oxidised nicotinamide adenine dinucleotide phosphate. Its products are -glucurono-3,6-lactone, [reduced NADPH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is L-gulono-1,4-lactone:NADP⁺ 1-oxidoreductase. Other names in common use include GRase, and gulonolactone dehydrogenase. This enzyme participates in ascorbate and aldarate metabolism.