General Director of Administrative Department of the Presidency
The General Director of Administrative Department of the Presidency is in charge of overseeing, managing, and executing the administrative tasks related to the presidency of Colombia, while also ensuring the effective implementation of government policies. In this role, the General Director leads the coordination between the Presidency and other state institutions, as well as civil society, and provides support to the President in fulfilling both constitutional and administrative duties.
List
List of general secretaries of the presidency
From its founding in 1898 until 2014, the highest position within the Administrative Department of the Presidency of the Republic was that of General Secretary of the Presidency, which changed its name in 2014 during the administration of Juan Manuel Santos.| Name | Assumed office | Left office | President(s) served under | |
| Rodrigo Lloreda | May 16, 1980 | August 7, 1981 | Julio César Turbay Ayala | |
| Germán Montoya | August 7, 1986 | August 7, 1990 | Virgilio Barco | |
| Alberto Velásquez Echeverri | July 6, 2005 | August 7, 2006 | Álvaro Uribe | |
| Bernardo Moreno | August 7, 2006 | August 7, 2010 | Álvaro Uribe | |
| Juan Carlos Pinzón | August 7, 2010 | September 5, 2011 | Juan Manuel Santos | |
| Federico Renjifo Vélez | September 8, 2011 | May 17, 2012 | Juan Manuel Santos | |
| Juan Mesa | May 20, 2017 | May 17, 2013 | Juan Manuel Santos | |
| Néstor Humberto Martínez | August 7, 2014 | June 15, 2015 | Juan Manuel Santos | |
| María Lorena Gutiérrez | June 18, 2015 | March 3, 2016 | Juan Manuel Santos | |
| Luis Guillermo Vélez | March 6, 2016 | March 25, 2017 | Juan Manuel Santos | |
| Alfonso Prada | March 28, 2017 | August 7, 2018 | Juan Manuel Santos | |
| Jorge Mario Eastman | August 7, 2018 | April 24, 2019 | Iván Duque |
List of general directors of DAPRE
In 2018, during Iván Duque administration, the position was restructured, taking on its current name of General Director of the Administrative Department of the Presidency.| Name | Assumed office | Left office | President(s) served under | |
| María Paula Correa | April 24, 2019 | October 2, 2019 | Iván Duque | |
| Diego Molano | October 3, 2019 | February 2, 2021 | Iván Duque | |
| Víctor Manuel Muñoz | February 2, 2021 | August 7, 2022 | Iván Duque | |
| Mauricio Lizcano | August 7, 2022 | May 1, 2023 | Gustavo Petro | |
| Carlos Ramón González | April 26, 2022 | February 23, 2024 | Gustavo Petro | |
| Laura Sarabia | February 23, 2024 | January 20, 2025 | Gustavo Petro | |
| Jorge Rojas | January 29, 2025 | February 5, 2025 | Gustavo Petro | |
| Angie Rodríguez | February 5, 2025 | January 13, 2026 | Gustavo Petro | |
| Nhora Mondragón | January 22, 2026 | Incumbent | Gustavo Petro |