GC
- Autopista GC-1
- Autovía GC-2
- Autovía GC-3
- Boss General Catalogue
- CG (disambiguation)
- Chat room
- Civil Guard (Spain)
- GC (gene)
- GC (video game character)
- GC-content
- GCS (disambiguation)
- Galactic Center
- Gallocatechol
- Gambia International Airlines
- GameCube
- Games Convention
- Garbage collection (computer science)
- Gas chromatography
- Gc (physics)
- Gemma Collins
- Gender critical
- General Catalyst
- General classification
- General contractor
- GenerativeComponents
- Genetic counselor
- George Cross
- Georgia Central Railway
- Germinal center
- Gigacoulomb
- Glass carbomer
- Glivenko–Cantelli theorem
- Global Catalog
- Glucocorticoid
- Go (programming language)
- Golden Corral
- Good Charlotte
- Google Classroom
- Goshen College
- Government of Canada
- Gran Canaria
- Grand Central (train operating company)
- Granular component
- Graphics card
- Grasshopper Club Zürich
- Green Council
- Greenland Cup
- Grinnell College
- Groupe Consultatif Actuariel Européen
- Guanylate cyclase
- Gurkha Contingent
- List of Allied convoy codes during World War II
- Mazda G platform
- Neisseria gonorrhoeae
- Subaru Impreza
- TERF
- The GC
- Unicode character property
- Unified Soil Classification System