Fructuronate reductase

In enzymology, fructuronate reductase is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are D-mannonic acid and oxidised nicotinamide adenine dinucleotide. Its products are D-fructuronic acid, reduced NADH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-mannonate:NAD⁺ 5-oxidoreductase. Other names in common use include mannonate oxidoreductase, mannonic dehydrogenase, D-mannonate dehydrogenase, and D-mannonate:NAD⁺ oxidoreductase. This enzyme participates in pentose and [glucuronate interconversions].