Francisco Ortega

• Francisco Ortega (bishop), Roman Catholic prelate
• Francisco Ortega (footballer, [born 1996)], Argentine defender for Atlético de Rafaela
• Francisco Ortega (footballer, born 1999), Argentine midfielder for Club Atlético Vélez Sarsfield
• Francisco Ortega (writer), Chilean writer
• Francisco Ortega III, Filipino politician
• Francisco Robles Ortega, Mexican prelate of the Catholic Church