Fladrafinil

Fladrafinil, also known as fluorafinil or as bisfluoroadrafinil, is a wakefulness-promoting agent related to modafinil that was never marketed. It is sold online and used non-medically as a nootropic.
Modafinil and its analogues are known to act as dopamine reuptake inhibitors and this is thought to be involved in their wakefulness-promoting effects. Chemically, fladrafinil is a derivative of adrafinil and is also known as bisfluoroadrafinil. It is closely related to flmodafinil.

Pharmacology

Pharmacodynamics

Fladrafinil has been found to produce antiaggressive effects in animals, which adrafinil does not produce. Fladrafinil is purportedly 3 to 4times more potent than adrafinil in this action.

Chemistry

Analogues

s of fladrafinil include modafinil, armodafinil, esmodafinil, adrafinil, flmodafinil, and CE-123, among others.

History

Fladrafinil appears to have first been patented in the 1980s.

Research

The pharmacokinetics of fladrafinil are being studied.