Fetal resorption
Fetal resorption is the disintegration and assimilation of one or more fetuses in the uterus at any stage after the completion of organogenesis, which, in humans, is after the ninth week of gestation. Before organogenesis, the process is called embryo resorption. Resorption is more likely to happen early on in the gestation than later on; a later death of a fetus is likely to result in a miscarriage.
In rodents
Fetal resorption in rats is common. Non-viable concepti are generally resorbed instead of being aborted like in humans. Factors that make it more common, sometimes to the point of infertility, include:- Vitamin E deficiency. In fact, this class of vitamin was originally identified by its lack causing infertility in rats. A deficiency of many other vitamins as well as some minerals such as copper can also cause fetal resorption.
- Administration of antiestrogens, removal of ovaries.
- Various other drugs or toxins including trypan blue and sweet peas.
- Inflammation caused by e.g. lipopolysaccharide, interleukin 4, and interleukin 12.