Enquatrovirus


Enquatrovirus is a genus of bacteriophages in the subfamily Enquatrovirinae, family Schitoviridae. Bacteria serve as natural hosts. There is only one species in this genus: Enquatrovirus N4.
Enquatrovirus N4 was originally isolated from sewers in Genoa, Italy and infects Escherichia coli K-12. Recently, a number of genetically related phages were isolated, infecting Silicibacter and Sulfitobacter as well as a number of Pseudomonas phages

Structure

The virus's virion have icosahedral heads ~70 nm and short tails, and contain short fibers originating from the junction between the head and tail. All the phages of this genus are strictly virulent and contain a linear dsDNA genome in the range of 70-75kb.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
EnquatrovirusHead-TailT=9Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by adsorption into the host cell. Dna templated transcription is the method of transcription. Bacteria serve as the natural host. Transmission routes are passive diffusion.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
EnquatrovirusBacteria-InjectionLysisCytoplasmCytoplasmPassive diffusion

RNA polymerases

A remarkable feature of this clade of phages is the use of three distinct RNA polymerases during its infection cycle. A giant virion-encapsulated RNAP polymerase which is co-injected, a heterodimeric phage RNA polymerase and the host RNA polymerase.