Elusive Copy Number Variation in the Mouse Genome
Elusive Copy Number Variation in the Mouse Genome is a scholarly work by Binnaz Yalçın, Amarjit Bhomra, Jonathan Flint, and Richard Mott, published in 2010 in ''PLOS One''. The main subjects of the publication include evolutionary biology, concordance, gene dosage, genome, genomic structural variation, Quantitative genetics, polyploidy, copy-number variation, biology, Copy number analysis, genetics, comparative genomic hybridization, computational biology, and base rate fallacy. The results indicate that CNVs detected by arrays may be the coincidental co-localization of smaller CNVs, whose presence is more likely to perturb an aCGH hybridization profile than the effect of an isolated, small, copy number alteration.