Edward O'Brien
Edward, Ed, Eddie or Ted O'Brien may refer to:
- Ed O'Brien, guitarist for Radiohead
- Sir Edward O'Brien, 2nd Baronet, Irish politician and baronet
- Edward Dominic O'Brien, Irish law enforcement official and British Army officer
- Sir Edward O'Brien, 4th Baronet, Irish politician and baronet
- Edward O'Brien, 14th Baron Inchiquin, Irish peer
- Edward Joseph Harrington O'Brien, American writer, poet, editor and anthologist
- Edward O'Brien (mural artist), American artist and muralist
- Edward O'Brien (athlete), American 400m runner
- Edward O'Brien (Irish republican), IRA member
- Edward Conor Marshall O'Brien, Irish aristocrat, architect and sailor
- Eddie O'Brien (baseball), American former Major League Baseball player
- Eddie O'Brien (hurler), Irish hurler
- Eddie O'Brien (footballer), Australian rules footballer
- Ted O'Brien, Australian politician
- Ted O'Brien (American politician)