List of earthquakes in 1921
This is a list of earthquakes in 1921. Only magnitude 6.0 or greater earthquakes appear on the list. Lower magnitude events are included if they have caused death, injury or damage. Events which occurred in remote areas will be excluded from the list as they wouldn't have generated significant media interest. All dates are listed according to UTC time. In a stark contrast to 1920, the death toll for this year was only 51. Dutch East Indies and Japan were very active.
Overall
By death toll
| Rank | Death toll | Magnitude | Location | MMI | Depth | Date |
| 1 | 51 | Italian Eritrea, off the coast of Massawa |
By magnitude
| Rank | Magnitude | Death toll | Location | MMI | Depth | Date |
| 1 | 0 |  Afghanistan|1919MMI-ts|desc=1|nts|240.0dts|November 15nts|7.6 |